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Carlo M Croce Selected Research

fragile histidine triad protein

1/2019Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells.
1/2013Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.
5/2008Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
6/2006Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
4/2006Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.
12/2005A mouse model of the fragile gene FHIT: From carcinogenesis to gene therapy and cancer prevention.
8/2005Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
11/2004Inactivation of the FHIT gene favors bladder cancer development.
3/2004Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
3/2002Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.

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Carlo M Croce Research Topics

Disease

314Neoplasms (Cancer)
01/2022 - 03/2002
56Carcinogenesis
10/2021 - 01/2003
41Leukemia
01/2022 - 11/2003
38B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
11/2019 - 11/2002
36Breast Neoplasms (Breast Cancer)
01/2022 - 03/2003
29Neoplasm Metastasis (Metastasis)
10/2021 - 10/2006
27Lung Neoplasms (Lung Cancer)
01/2020 - 02/2003
18Lymphoma (Lymphomas)
10/2016 - 01/2005
16Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 03/2008
15Hepatocellular Carcinoma (Hepatoma)
03/2018 - 07/2007
14Carcinoma (Carcinomatosis)
01/2019 - 03/2002
13Hematologic Neoplasms (Hematological Malignancy)
01/2022 - 08/2005
11Colorectal Neoplasms (Colorectal Cancer)
10/2021 - 08/2007
11Inflammation (Inflammations)
01/2020 - 10/2008
10Esophageal Neoplasms (Esophageal Cancer)
03/2016 - 10/2004
9Prostatic Neoplasms (Prostate Cancer)
02/2021 - 07/2006
8Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021 - 02/2003
8Triple Negative Breast Neoplasms
01/2020 - 08/2012
8Adenocarcinoma
01/2015 - 05/2004
7Pancreatic Neoplasms (Pancreatic Cancer)
12/2018 - 09/2004
7Glioblastoma (Glioblastoma Multiforme)
01/2017 - 04/2012
7B-Cell Lymphoma (Lymphoma, B Cell)
01/2017 - 09/2005
7Colonic Neoplasms (Colon Cancer)
01/2014 - 06/2006
7Ovarian Neoplasms (Ovarian Cancer)
06/2013 - 02/2003
7Infections
10/2007 - 11/2004
6Esophageal Squamous Cell Carcinoma
10/2017 - 07/2003
6Disease Progression
01/2017 - 10/2005
6Ovarian Epithelial Carcinoma
11/2016 - 09/2007
6Urinary Bladder Neoplasms (Bladder Cancer)
06/2014 - 11/2004
6Chromosome Aberrations (Chromosome Abnormalities)
07/2011 - 05/2007
5Sarcoma (Soft Tissue Sarcoma)
01/2016 - 01/2005
5Liver Neoplasms (Liver Cancer)
09/2012 - 07/2008
5Stomach Neoplasms (Stomach Cancer)
02/2010 - 05/2004
4Cachexia
01/2020 - 03/2014
4Hypoxia (Hypoxemia)
01/2016 - 03/2007
4BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
10/2013 - 06/2008
4Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
05/2010 - 06/2005
4Adenoma (Adenomas)
02/2007 - 05/2002
3Melanoma (Melanoma, Malignant)
01/2018 - 01/2016
3Multiple Myeloma
01/2016 - 09/2008
3Inborn Genetic Diseases (Disease, Hereditary)
07/2015 - 09/2007

Drug/Important Bio-Agent (IBA)

248MicroRNAs (MicroRNA)IBA
01/2022 - 11/2002
82Proteins (Proteins, Gene)FDA Link
10/2021 - 07/2002
45Biomarkers (Surrogate Marker)IBA
10/2021 - 01/2003
26Biological ProductsIBA
10/2021 - 03/2003
21Messenger RNA (mRNA)IBA
07/2020 - 04/2003
17DNA (Deoxyribonucleic Acid)IBA
01/2016 - 04/2005
16RNA (Ribonucleic Acid)IBA
01/2020 - 10/2004
14Pharmaceutical PreparationsIBA
01/2022 - 10/2005
14CarcinogensIBA
01/2020 - 09/2003
13ZincIBA
10/2017 - 01/2003
11Histidine (L-Histidine)FDA Link
10/2014 - 03/2002
10WW Domain-Containing OxidoreductaseIBA
01/2020 - 02/2003
10fragile histidine triad proteinIBA
01/2019 - 03/2002
9nitrosobenzylmethylamineIBA
01/2020 - 01/2003
8Phosphotransferases (Kinase)IBA
10/2013 - 05/2007
7Transcription Factors (Transcription Factor)IBA
01/2020 - 11/2004
7Untranslated RNA (Noncoding RNA)IBA
01/2019 - 09/2007
7mouse MIRN29 microRNAIBA
08/2012 - 06/2009
6Transfer RNA (tRNA)IBA
01/2020 - 01/2017
6Caspase 3 (Caspase-3)IBA
12/2018 - 07/2002
6LigandsIBA
01/2018 - 09/2007
6Tyrosine (L-Tyrosine)FDA Link
10/2012 - 04/2005
6OligonucleotidesIBA
09/2012 - 12/2005
6NucleotidesIBA
07/2012 - 11/2003
5Antineoplastic Agents (Antineoplastics)IBA
07/2020 - 09/2010
5Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2019 - 07/2002
5AntigensIBA
01/2018 - 04/2013
5Long Noncoding RNAIBA
01/2018 - 01/2014
5ErbB Receptors (EGF Receptor)IBA
01/2018 - 07/2009
5CaspasesIBA
11/2015 - 10/2004
5Histone Deacetylase InhibitorsIBA
11/2014 - 07/2006
4Small Untranslated RNAIBA
01/2022 - 06/2004
4NucleolinIBA
07/2020 - 05/2013
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2016 - 01/2009
4NucleophosminIBA
04/2014 - 03/2008
4MethyltransferasesIBA
06/2013 - 07/2006
4DecitabineFDA Link
02/2013 - 07/2006
4NF-kappa B (NF-kB)IBA
07/2010 - 11/2008
3Receptor Tyrosine Kinase-like Orphan ReceptorsIBA
01/2021 - 01/2014
33' Untranslated Regions (3' UTR)IBA
04/2019 - 12/2008
3Ferredoxins (Ferredoxin)IBA
01/2019 - 05/2008
3Oxidoreductases (Dehydrogenase)IBA
01/2019 - 05/2008
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2019 - 05/2008
3PlatinumIBA
12/2018 - 12/2008
3Folic Acid (Vitamin M)FDA LinkGeneric
01/2018 - 06/2015
3EnzymesIBA
10/2017 - 10/2007
3Paclitaxel (Taxol)FDA LinkGeneric
05/2016 - 01/2013
3Peptides (Polypeptides)IBA
05/2016 - 10/2012
3Estrogen Receptor alphaIBA
01/2015 - 05/2010
3Tyrosine Kinase InhibitorsIBA
10/2013 - 07/2009
3ChromatinIBA
10/2013 - 12/2008
3Insulin (Novolin)FDA Link
09/2013 - 07/2005
3trichostatin A (A 300)IBA
02/2013 - 07/2006
3Phosphoric Monoester Hydrolases (Phosphatases)IBA
10/2012 - 01/2010
3Protein Tyrosine PhosphatasesIBA
10/2012 - 06/2006

Therapy/Procedure

72Therapeutics
01/2021 - 05/2002
11Drug Therapy (Chemotherapy)
01/2020 - 05/2007
3Chemoprevention
02/2018 - 05/2006
3Immunotherapy
12/2016 - 10/2016